Annual report pursuant to Section 13 and 15(d)

Summary of Significant Accounting Policies - Intangible Assets, Long-lived Assets, Advertising and Research and Development Costs (Details)

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Summary of Significant Accounting Policies - Intangible Assets, Long-lived Assets, Advertising and Research and Development Costs (Details) - USD ($)
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Intangible Asset disclosures    
Impairment charges of long lived assets $ 0 $ 0
Advertising costs 31,000 8,000
Research and development $ 3,237,171 $ 3,033,325
Licensing Agreements and Patents [Member] | Minimum    
Intangible Asset disclosures    
Estimated useful life 5 years  
Licensing Agreements and Patents [Member] | Maximum    
Intangible Asset disclosures    
Estimated useful life 20 years