Annual report pursuant to Section 13 and 15(d)

Intangible Assets - Components of Intangible Assets (Details)

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Intangible Assets - Components of Intangible Assets (Details) - USD ($)
 12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Intangible assets consist of:    
Less: accumulated amortization $ (463,575) $ (399,509)
Intangible assets, net 828,979 678,082
Amortization of Intangible Assets 74,871 45,828
Impairment charges of long lived assets 0 0
Licensing Agreements    
Intangible assets consist of:    
Finite-lived intangible assets, gross $ 984,342 897,594
Licensing Agreements | Minimum    
Intangible assets consist of:    
Amortization period of intangible assets 17 years  
Licensing Agreements | Maximum    
Intangible assets consist of:    
Amortization period of intangible assets 20 years  
Patents    
Intangible assets consist of:    
Finite-lived intangible assets, gross $ 308,212 $ 179,997
Amortization period of intangible assets 3 years  
Non-amortizable pending costs $ 308,212