Annual report pursuant to Section 13 and 15(d)

CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (DEFICIT)

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CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (DEFICIT) - USD ($)
Common Stock [Member]
Additional Paid-in Capital [Member]
Retained Earnings [Member]
Total
Beginning Balance at Dec. 31, 2014 $ 194,888 $ 78,675,686 $ (90,116,254) $ (11,245,680)
Beginning Balance (in shares) at Dec. 31, 2014 19,488,814      
Increase (Decrease) in Stockholders' Equity        
Stock-based compensation   1,316,509   1,316,509
Exercise of stock options $ 1,975 510,826   512,801
Exercise of stock options (in shares) 197,466      
Issuance of common shares $ 102,983 30,865,403   30,968,386
Issuance of common shares (in shares) 10,298,311      
Net loss     (13,356,425) (13,356,425)
Ending Balance at Dec. 31, 2015 $ 299,846 111,368,424 (103,472,679) $ 8,195,591
Ending Balance (in shares) at Dec. 31, 2015 29,984,591     29,984,591
Increase (Decrease) in Stockholders' Equity        
Stock-based compensation   1,390,277   $ 1,390,277
Exercise of stock options $ 3,409 1,074,924   1,078,333
Exercise of stock options (in shares) 340,940      
Issuance of common shares $ 26,833 18,641,259   18,668,092
Issuance of common shares (in shares) 2,683,334      
Net loss     (14,411,144) (14,411,144)
Ending Balance at Dec. 31, 2016 $ 330,088 $ 132,474,884 $ (117,883,823) $ 14,921,149
Ending Balance (in shares) at Dec. 31, 2016 33,008,865     33,008,865